Simon Hughes
Consultant clinical oncologist
Biography
Simon Hughes was appointed as a clinical oncology consultant at Guy’s and St Thomas’ hospitals in 2008. He treats urological cancers, with a focus on novel radiotherapy techniques and the combination of systemic therapy with radiotherapy. He is the UK lead for the ENZARAD and DASL-HiCAP studies and is developing an HDR brachytherapy programme for bladder cancer.
His other passion is clinical education. He is chief medical officer for The Learning Lab (an NHS spinout from Guy’s and St Thomas’ hospitals), founded Guy’s Cancer Academy, and holds various education roles within the American Society of Clinical Oncology.
Education and training
- Fellowship of the Academy of Medical Educators, 2020
- Fellowship of the Higher Education Academy, 2017
- Fellowship of the Royal College of Physicians, London, 2013
- Doctor of medicine by research (MD(Res)), University of London, 2010
- Fellowship of the Royal College of Radiologists, 2005
- Bachelor of Medicine, Bachelor of Surgery (MBBS), University of London, 1997
- Anatomy and basic medical sciences BSc (Hons), First Class Honours, University of London, 1994
Research interests
- Combining novel agents with radiotherapy
- Radiotherapy techniques to account for tumour motion
- Radiotherapy dose escalation and de-escalation
- Incorporating functional imaging into radiotherapy planning
- Application of learning science principles to clinical education
Last updated: September 2026