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Extracorporeal photopheresis

The treatment of blood using ultraviolet light


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About us

St John's Institute of Dermatology at Guy's and St Thomas' Hospital was the first centre in the United Kingdom to offer photopheresis treatment with over 20 years of experience. At present, it is the biggest and busiest ECP nurse led centre in the world with a capacity of 24 treatments a day, 124 treatments a week operating from Monday to Saturday, 8am to 7pm. We are located at Guy's Cancer Centre, Chemotherapy Village Level C1.

Extracorporeal photopheresis (ECP) is a cell‐based immuno-modulatory therapy involving the separation of white blood cell‐rich plasma (buffy coat) followed by administration of a photosensitiser (methoxsalen) and ultraviolet A (UVA) radiation before re‐infusion. It is used to treat a range of diseases. At Guy's and St Thomas' it is a treatment for Cutaneous T-cell lymphoma (a rare type of lymphoma that affects the skin) and Sezary Syndrome (a form of Cutaneous T-cell lymphoma) and is also used as a second line therapy in the management of acute and chronic Graft versus Host Disease (GvHD) following stem cell transplantation.

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Tel: 020 7188 6308

Email: ECPPhotopheresis